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My Cat's Skin Is Turning Yellow — Hepatic Lipidosis Case

A 10-year-old obese DSH stopped eating 5 days ago after stress. Now jaundiced. Hepatic lipidosis is the most common cause of liver failure in cats.

9 min read2026-01-24
hepatic lipidosiscat jaundicecat not eatingfatty liver
PetMed AI Veterinary TeamVerified

Reviewed by Licensed DVM Professionals

Evidence-BasedPeer-Reviewed SourcesLast updated: 2026-01-24
Case Presentation

Your 10-year-old obese DSH, Buttercup, stopped eating 5 days ago after a move. She's lost weight and now her ears, gums, and skin are yellow. She's lethargic and dehydrated. What's happening?

10 yr
Age
Obese
Body Condition
5 days
Anorexia
Jaundice
Icterus

Warning: Hepatic lipidosis is life-threatening. Obese cats who stop eating mobilize fat to the liver, causing liver failure. Jaundice indicates severe disease. Aggressive nutritional support is essential—without it, mortality is high.

🩺 Pathophysiology

When cats stop eating, fat is mobilized from adipose tissue. The feline liver cannot process large fat loads—fat accumulates in hepatocytes, causing cholestasis and liver failure. The Bloodwork OCR helps interpret elevated ALT, ALP, bilirubin. The Internal Medicine Specialist explains: Obese cat + anorexia + jaundice = hepatic lipidosis. Feeding tube and supportive care.

💊 Treatment

Nutritional support is the cornerstone—often via feeding tube (esophagostomy or nasogastric). Appetite stimulants alone are insufficient. The Feline Medicine Specialist outlines protocols. Recovery takes 4–8 weeks. Identify and address the inciting cause (stress, illness). With aggressive support, survival is 80–90%.

Use Bloodwork OCR, Internal Medicine Specialist, and Feline Medicine Specialist for hepatic lipidosis workup.


Key Takeaways
  • Obese cat + anorexia + jaundice = hepatic lipidosis.
  • Nutritional support is essential—feeding tube often required.
  • Recovery takes weeks—patience and commitment.
  • Find the inciting cause—stress, illness, diet change.
  • Never let an obese cat go 24–48 hours without eating—intervene early.

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